Laboratory of Biotechnology and Immunodiagnostics of High Dangerous Pathogens
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Head of laboratory: SEMIZHON Pavel PhD
Tel.: +375-172 68 04 19 E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
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Scientific interest
Scientific investigations. The study of the molecular and biological properties and characteristics of the main representatives of highly dangerous Filo-, Arena -, Hanta-, and Henipaviruses; development and improvement of molecular biological and immunological diagnostic test-systems, and their components; improvement of recombinant technologies; epidemiological surveillance of natural focal infections.
Practical activities: Production of ELISA-, PCR-test-systems and their components, medical kits for the isolation of nucleic acids.
Staff Researchers
Alexander S. Vladyko Chief researcher, MD, PhD, |
Helena P. Scheslenok Leading researcher, PhD |
Tatjana V. Shkolina Scientific researcher |
Nikita A. Dubkov Scientific researcher |
![]() Ekaterina Y. Burdeyko Junior researcher |
![]() Tatyana N. Kasnitskaya Junior researcher |
Main area of researches:
- Development of immuno - and molecular-biological diagnostic kits for highly dangerous pathogens (Lassa, Marburg, Ebola, Hendra, Nipah) and other viral and bacterial infections (lymphocytic choriomeningitis (LCM), tick-borne encephalitis (TBE), West Nile (WN), Congo-Crimian hemorrhagic fever (CCHF), hemorrhagic fever with renal syndrome (HFRS), dengue fever, hepatitis C and others);
- Peptide mapping structural and non-structural proteins of viral and bacterial pathogens to develop of new diagnostic methods;
- Development of new technologies in the field of epidemiology to clear the causes and mechanisms of the “disease X” appearance;
- Creation of recombinant plasmid vectors to produce the recombinant peptides of antigen-significant sites of highly dangerous pathogens;
- Training of scientific personnel in the field of Virology;
- Advisory and methodological assistance to practical medicine.
The direction of the research (project) |
Time of performance |
Volume of financing, EURO |
Expected result |
"Development of technological platform for epidemiological forecasting of new and emerging infectious diseases»
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2020- 2025 |
250.000
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A complex multiplex diagnosticum for seroepidemiological and molecular biological studies of biocenotic systems in the territory of the Any Country will be developed. The introduction of the technology will create a basis for the systematic analysis and prediction of infections in the field of Biosafety of the country. |
“Development of a multiplex immunoassay diagnostic test system to identify simultaneously markers of hepatitis C, B, HIV, LCM, WNV viruses, syphilis, etc.” |
2020- 2025 |
250.000
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The test system can be used in blood transfusion and transplantation |
“Development of personalized immunocorrection technology to create an individual vaccine” |
2020- 2025 |
250.000
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It is planned to determine the spectrum of antibodies with further stimulation of their individual clones based on the use of peptide molecular motifs derived from bacteria (second genome). |